{"id":387,"date":"2022-07-25T14:39:46","date_gmt":"2022-07-25T12:39:46","guid":{"rendered":"https:\/\/oncoact.nl\/?page_id=387"},"modified":"2024-10-31T09:23:59","modified_gmt":"2024-10-31T08:23:59","slug":"patient","status":"publish","type":"page","link":"https:\/\/oncoact.nl\/en\/patient\/","title":{"rendered":"Patient"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"645\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/silhouette@2x-1920x1209-1-1024x645.png\" alt=\"\" class=\"wp-image-23\" srcset=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/silhouette@2x-1920x1209-1-1024x645.png 1024w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/silhouette@2x-1920x1209-1-300x189.png 300w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/silhouette@2x-1920x1209-1-768x484.png 768w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/silhouette@2x-1920x1209-1-1536x967.png 1536w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/silhouette@2x-1920x1209-1.png 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Importance of<em>&nbsp;Complete DNA Analysis<\/em>&nbsp;in the Care of Cancer Patients<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Cancer is a disease that is largely caused by changes in the DNA. These changes can have several causes. Each tumor is unique and has specific characteristics that are different for each patient and each tumor type. At the moment, many patients are given medication that focuses on the tumor type (colon cancer, lung cancer, etc.). In an increasing number of cases, the choice of medication is also determined by the individual characteristics of the tumor. In a number of cases this involves genetic characteristics.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">More and more personalised treatments that examine the unique DNA profile of the tumor are possible.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Molecular Diagnostics<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In order to \u201cread\u201d the unique profile of the tumor, high-quality molecular diagnostics are required. These diagnostics are currently performed in different ways and with different techniques. OncoAct consists of:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>a molecular diagnostic DNA test;<\/li>\n\n\n\n<li>a report containing the tumor\u2019s characteristics;<\/li>\n\n\n\n<li>a recommendation for possible treatments.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This creates a more comprehensive overview of the treatment options for the patient.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">By using this DNA test, options for participation in clinical studies or experimental treatments can also be identified.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"768\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/NovaSeq-sequencers-1920x1440-1-1024x768.jpg\" alt=\"\" class=\"wp-image-25\" srcset=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/NovaSeq-sequencers-1920x1440-1-1024x768.jpg 1024w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/NovaSeq-sequencers-1920x1440-1-300x225.jpg 300w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/NovaSeq-sequencers-1920x1440-1-768x576.jpg 768w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/NovaSeq-sequencers-1920x1440-1-1536x1152.jpg 1536w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/NovaSeq-sequencers-1920x1440-1.jpg 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\"><br><\/figcaption><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Complete-DNA-test-1024x683.jpg\" alt=\"\" class=\"wp-image-28\" srcset=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Complete-DNA-test-1024x683.jpg 1024w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Complete-DNA-test-300x200.jpg 300w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Complete-DNA-test-768x512.jpg 768w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Complete-DNA-test-1536x1024.jpg 1536w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Complete-DNA-test.jpg 1920w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Complete DNA-test: OncoAct<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">OncoAct is the most extensive molecular diagnostic DNA test. It allows us to read the entire DNA using a technique called&nbsp;<a href=\"https:\/\/oncoact.nl\/how-does-oncoact-work\/?lang=en#wholegenomesequencing\"><em>whole genome sequencing<\/em><\/a>.&nbsp;The DNA test provides insight into the complete genetic profile of the cancer.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The personalized OncoAct WGS report that is provided with the DNA test helps answer an important question: are there any medication or treatment options for me based on the specific characteristics of my tumor?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The OncoAct WGS report gives an overview of possible treatments. Any clinical studies (scientific studies) in the Netherlands in which the patient can participate will also be mentioned.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">More Information about DNA Research in Cancer<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Information about DNA testing for cancer can also be found on the website of&nbsp;<a href=\"http:\/\/www.kanker.nl\/\">kanker.nl<\/a>:<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-9cdb7320 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.kanker.nl\/algemene-onderwerpen\/dna-onderzoek-bij-mensen-met-kanker\/waarom-krijg-ik-dna-onderzoek\/redenen-voor-dna-onderzoek\">Reasons for DNA-research<\/a><\/div>\n\n\n\n<div class=\"wp-block-button is-style-outline is-style-outline--2\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.kanker.nl\/algemene-onderwerpen\/dna-onderzoek-bij-mensen-met-kanker\/waarom-krijg-ik-dna-onderzoek\/dna-onderzoek-bij-het-kiezen-voor-een-behandeling\">DNA-testing when choosing a treatment<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">How is the Decision About the Treatment Made?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In addition to the results of the complete DNA analysis, the results of other tests are also important when making a decision about the treatment. These are tests carried out in the hospital by the pathology, clinical chemistry, and radiology departments. In the consultation with your treating physician about your treatment, your personal characteristics and wishes are important.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns background-pattern is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">Is OncoAct the Best DNA Test for Me?<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h3 class=\"wp-block-heading\"><strong>Treating Physician<\/strong><\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Why apply&nbsp;<a href=\"https:\/\/oncoact.nl\/how-does-oncoact-work\/?lang=en#wholegenomesequencing\"><em>whole genome sequencing<\/em><\/a>&nbsp;to DNA testing in the care of cancer patients?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Whether OncoAct is useful and suitable and whether tumour tissue can be safely removed will be determined in consultation with the treating physician. They know you and your background best. In order to perform the DNA test, tumor tissue and blood will have to be collected in the hospital.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h3 class=\"wp-block-heading\">Solid tumour<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">In principle, OncoAct is suitable for all patients with cancer, with the exception of patients with leukemia. The complete DNA test requires a tumor sample to be taken from a patient. This is frozen instantly in a special way and can then be analysed.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The following patients can benefit most from the complete DNA test:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>patients who no longer have any treatment options available based on regular diagnostics<\/li>\n\n\n\n<li>patients with a rare tumour (approximately 23,000 in the Netherlands) for whom no standard treatment is available<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h3 class=\"wp-block-heading\">Molecular Diagnostic DNA Tests<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Various molecular diagnostic DNA tests are already being performed in the current care of patients with cancer. These DNA tests vary depending on the hospital and usually focus on a limited number of tumor characteristics. For a significant number of patients with tumors, molecular diagnostic DNA tests are not yet being conducted according to current guidelines because no registered targeted drugs exist for these tumor types.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">OncoAct is not yet part of the basic package and is generally not reimbursed by the health insurer.&nbsp;<a href=\"https:\/\/www.hartwigmedicalfoundation.nl\/en\/\">Hartwig Medical Foundation<\/a>&nbsp;is one of several organisations working hard to make that happen<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns background-blue is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"151\" height=\"151\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/ICON-REPORT.png\" alt=\"\" class=\"wp-image-107\"\/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">OncoAct WGS report<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">With OncoAct, the treating physician receives an OncoAct WGS report containing all treatments that may be suitable for the patient, including both registered and non-registered medications, and clinical studies.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group background-lightgray\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h2 class=\"wp-block-heading\">How does OncoAct Work for You?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">OncoAct can only be requested by your treating physician at a hospital. How do you proceed?<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column card-patient is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\">01<\/h4>\n\n\n\n<h3 class=\"wp-block-heading\">Discuss it with your physician<\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"151\" height=\"151\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/ICON-DOCTOR.png\" alt=\"\" class=\"wp-image-114\"\/><figcaption class=\"wp-element-caption\">Discuss it with your physician<br><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Discuss your treatment options with your treating physician. If OncoAct is an option for you, your physician will request it from Hartwig Medical Foundation. It is important to know if your doctor can request the extensive DNA test from Hartwig Medical Foundation.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column card-patient is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\">02<\/h4>\n\n\n\n<h3 class=\"wp-block-heading\">At the hospital<\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"151\" height=\"151\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/ICON-HOSPITAL.png\" alt=\"\" class=\"wp-image-115\"\/><figcaption class=\"wp-element-caption\">At the hospital<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Tumor tissue and blood is taken at the hospital. Your treating physician will send them to Hartwig Medical Foundation.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column card-patient is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\">03<\/h4>\n\n\n\n<h3 class=\"wp-block-heading\">DNA analysis<\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"151\" height=\"151\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/ICON-BUIS.png\" alt=\"\" class=\"wp-image-116\"\/><figcaption class=\"wp-element-caption\">DNA analysis<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Hartwig Medical Foundation conducts the extensive DNA test on tumor tissue and blood. This is followed by a bioinformatic data analysis. The results are included in a patient report with a summary and explanation by a clinical molecular biologist of the pathology department.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column card-patient is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\">04<\/h4>\n\n\n\n<h3 class=\"wp-block-heading\">OncoAct WGS report<\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"151\" height=\"151\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/ICON-REPORT.png\" alt=\"\" class=\"wp-image-107\"\/><figcaption class=\"wp-element-caption\">OncoAct WGS report<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Your treating physician will usually receive your OncoAct WGS report within two to three weeks of the tumor tissue and blood arriving at Hartwig Medical Foundation.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column card-patient is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\">05<\/h4>\n\n\n\n<h3 class=\"wp-block-heading\">Discussing the report<\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"151\" height=\"151\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/ICON-DNA-1.png\" alt=\"\" class=\"wp-image-117\"\/><figcaption class=\"wp-element-caption\">Discussing the report<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">You discuss the results of the OncoAct WGS report with your treating physician and discuss the next step in your treatment.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-columns background-blue is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"block-quotes\">\r\n\r\n        \r\n    <div class=\"container\">\r\n    <div class=\"row align-items-center justify-content-center\">\r\n      <div class=\"col-lg-7\">\r\n        <img loading=\"lazy\" decoding=\"async\" width=\"754\" height=\"753\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Veronica-van-Nederveen-Vierkant.jpg\" class=\"quote-photo\" alt=\"\" srcset=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Veronica-van-Nederveen-Vierkant.jpg 754w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Veronica-van-Nederveen-Vierkant-300x300.jpg 300w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Veronica-van-Nederveen-Vierkant-150x150.jpg 150w\" sizes=\"auto, (max-width: 754px) 100vw, 754px\" \/>        <div class=\"quote\">\n<p class=\"wp-block-paragraph\">The comprehensive DNA test provides a complete overview of all potential targeted cancer treatments. This means the patient and the treating physician have all available information at their fingertips to make a treatment decision together.<\/p>\n<\/div>\r\n        <div class=\"quote-author\">\r\n          &mdash; Veronica van Nederveen<br \/>\r\n          <span><\/span>\r\n        <\/div>\r\n      <\/div>\r\n    <\/div>\r\n  <\/div>\r\n    <\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><div class=\"block-quotes\">\r\n\r\n        \r\n    <div class=\"container\">\r\n    <div class=\"row align-items-center justify-content-center\">\r\n      <div class=\"col-lg-7\">\r\n        <img loading=\"lazy\" decoding=\"async\" width=\"776\" height=\"776\" src=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Anne-van-Herwijnen-Vierkant-sRGB.jpg\" class=\"quote-photo\" alt=\"\" srcset=\"https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Anne-van-Herwijnen-Vierkant-sRGB.jpg 776w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Anne-van-Herwijnen-Vierkant-sRGB-300x300.jpg 300w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Anne-van-Herwijnen-Vierkant-sRGB-150x150.jpg 150w, https:\/\/oncoact.nl\/wp-content\/uploads\/2022\/07\/Anne-van-Herwijnen-Vierkant-sRGB-768x768.jpg 768w\" sizes=\"auto, (max-width: 776px) 100vw, 776px\" \/>        <div class=\"quote\">\n<p class=\"wp-block-paragraph\">From my own experience, I know how important knowledge of hereditary predisposition to cancer can be. This is why I think it is so important that comprehensive patient reports include precisely that carrier information (if the patient wishes to be informed).<\/p>\n<\/div>\r\n        <div class=\"quote-author\">\r\n          &mdash; Anne van Herwijnen<br \/>\r\n          <span><\/span>\r\n        <\/div>\r\n      <\/div>\r\n    <\/div>\r\n  <\/div>\r\n    <\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Importance of&nbsp;Complete DNA Analysis&nbsp;in the Care of Cancer Patients Cancer is a disease that is largely caused by changes in &hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-387","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Patient - Hartwig Medical OncoAct<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/oncoact.nl\/en\/patient\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Patient - 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